Radical Nephrectomy vs Partial Nephrectomy

As presented by Huang, et al., patients that receive a Radical Nephrectomy have a 5-yr survival rate of 38% less than their peers having undergone a Partial Nephrectomy instead.  These patients are also 1.4x more likely to experience a cardiac event such as a stroke or heart attack.  Radical Nephrectomy patients also experience much higher rates of Renal Insufficiency or Renal Failure, being on dialysis, and taking numerous adjuvant drug therapies.[2,3]  For these reasons, both the American Urologic Association (AUA) and the European Association of Urology (EAU) recommend the use of Partial Nephrectomy whenever feasible.[4,5]

Radical vs. Partial Nephrectomy

Sources: Lowrance (2010); Huang (2009); Thompson (2008).